| date | Pair 1 | sets | Pair 2 | set 1 | set 2 | set 3 | dur (pts) |
| Sun 14.02.21 | Marcelo Arevalo / Matwe Middelkoop |  ESA |  NED | | 2-1 | Alexander Bublik / Anfrey Golubev |  KAZ | KAZ | | 6-74 | 7-63 | 6-3 | 2:23 (118-105) |
| Mon 15.02.21 | Jamie Murray / Bruno Soares |  GBR |  BRA | 6 | 2-1 | Simone Bolelli / Maximo Gonzalez |  ITA |  ARG | | 6-75 | 6-2 | 6-4 | 2:34 (108-98) |
| Sun 14.02.21 | Marcus Daniell / Philipp Oswald |  NZL |  AUT | | 2-0 | Nicholas Monroe / Frances Tiafoe |  USA | USA | | 6-3 | 7-5 | | 1:28 (77-61) |
| Mon 15.02.21 | Rajeev Ram / Joe Salisbury | USA | GBR | 5 | 2-0 | John Peers / Michael Venus |  AUS | NZL | 10 | 7-64 | 7-64 | | 1:51 (85-82) |
| Mon 15.02.21 | Ivan Dodig / Filip Polasek |  CRO |  SVK | 9 | 2-0 | Marcelo Melo / Horia Tecau | BRA |  ROU | 7 | 6-4 | 6-3 | | 1:27 (68-55) |
| Mon 15.02.21 | Matthew Ebden / John-Patrick Smith | AUS | AUS | WC | 2-0 | Wesley Koolhof / Lukasz Kubot | NED |  POL | 4 | 7-62 | 6-4 | | 1:37 (73-62) |
| Sun 14.02.21 | Pierre-Hugues Herbert / Nicolas Mahut |  FRA | FRA | 8 | 2-0 | James Duckworth / Marc Polmans | AUS | AUS | WC | 6-4 | 6-3 | | 1:16 (67-54) |
| Sun 14.02.21 | Nikola Mektic / Mate Pavic | CRO | CRO | 2 | 2-0 | John Millman / Thiago Monteiro | AUS | AUS | | 7-63 | 6-4 | | 1:15 (71-56) |
| date | Pair 1 | sets | Pair 2 | set 1 | set 2 | set 3 | dur (pts) |
| Sat 13.02.21 | Alexander Bublik / Anfrey Golubev | KAZ | KAZ | | 2-0 | Juan Sebastian Cabal / Robert Farah |  COL | COL | 1 | 6-4 | 6-4 | | 1:12 (65-50) |
| Fri 12.02.21 | Marcelo Arevalo / Matwe Middelkoop | ESA | NED | | 2-0 | Miomir Kecmanovic / Casper Ruud |  SRB |  NOR | | 6-3 | 6-1 | | 0:52 (53-38) |
| Fri 12.02.21 | Simone Bolelli / Maximo Gonzalez | ITA | ARG | | 2-0 | Lorenzo Sonego / Andres Vavassori | ITA | ITA | | 6-2 | 7-65 | | 1:30 (72-54) |
| Fri 12.02.21 | Jamie Murray / Bruno Soares | GBR | BRA | 6 | 2-0 | Laslo Djere / Stefano Travaglia | SRB | ITA | | 6-1 | 6-2 | | 1:00 (61-38) |
| Sat 13.02.21 | Nicholas Monroe / Frances Tiafoe | USA | USA | | 2-1 | Vasek Pospisil / Denis Shapovalov |  CAN | CAN | | 2-6 | 7-69 | 6-2 | 2:02 (95-95) |
| Sat 13.02.21 | Marcus Daniell / Philipp Oswald | NZL | AUT | | 2-1 | Dominik Koepfer / Tennys Sandgren |  GER | USA | | 7-64 | 6-73 | 6-2 | 2:08 (113-94) |
| Fri 12.02.21 | John Peers / Michael Venus | AUS | NZL | 10 | 2-0 | Nam Ji-Sung / Song Min-Kyu |  KOR | KOR | WC | 6-4 | 6-3 | | 1:11 (63-54) |
| Sat 13.02.21 | Rajeev Ram / Joe Salisbury | USA | GBR | 5 | 2-1 | Tomislav Brkic / Aisam Ul-Haq Qureshi |  BIH |  PAK | | 6-3 | 4-6 | 6-2 | 1:49 (83-65) |
| Sat 13.02.21 | Marcelo Melo / Horia Tecau | BRA | ROU | 7 | 2-0 | Radu Albot / Daniel Evans |  MDA | GBR | | 6-1 | 7-62 | | 1:15 (74-48) |
| Sat 13.02.21 | Ivan Dodig / Filip Polasek | CRO | SVK | 9 | 2-0 | Luke Bambridge / Dominic Inglot | GBR | GBR | | 6-4 | 7-5 | | 1:20 (67-49) |
| Fri 12.02.21 | Matthew Ebden / John-Patrick Smith | AUS | AUS | WC | 2-0 | Max Purcell / Luke Saville | AUS | AUS | 15 | 7-63 | 6-4 | | 1:32 (73-63) |
| Sun 14.02.21 | Wesley Koolhof / Lukasz Kubot | NED | POL | 4 | 2-0 | Thanasi Kokkinakis / Nick Kyrgios | AUS | AUS | WC | 6-3 | 6-2 | | 1:10 (59-49) |
| Fri 12.02.21 | Pierre-Hugues Herbert / Nicolas Mahut | FRA | FRA | 8 | 2-0 | Yannick Hanfmann / Kevin Krawietz | GER | GER | | 7-5 | 6-3 | | 1:12 (57-45) |
| Fri 12.02.21 | James Duckworth / Marc Polmans | AUS | AUS | WC | 2-0 | Richard Berankis / Mikhail Kukushkin |  LTU | KAZ | | 7-63 | 6-2 | | 1:22 (71-61) |
| Sat 13.02.21 | John Millman / Thiago Monteiro | AUS | BRA | | 2-1 | Ken Skupski / Neal Skupski | GBR | GBR | 16 | 3-6 | 7-65 | 6-4 | 2:00 (91-89) |
| Fri 12.02.21 | Nikola Mektic / Mate Pavic | CRO | CRO | 2 | 2-0 | Mackenzie McDonald / Tommy Paul | USA | USA | | 6-1 | 6-4 | | 0:54 (58-36) |
| date | Pair 1 | sets | Pair 2 | set 1 | set 2 | set 3 | dur (pts) |
| Thu 11.02.21 | Juan Sebastian Cabal / Robert Farah | COL | COL | 1 | 2-1 | Nikoloz Basilashvili / Andre Begemann |  GEO | GER | | 6-75 | 7-66 | 6-4 | 2:49 (133-127) |
| Fri 12.02.21 | Alexander Bublik / Anfrey Golubev | KAZ | KAZ | | 2-0 | S Caruso / E Ruusuvuori | ITA |  FIN | ALT | 7-66 | 7-5 | | 1:31 (78-76) |
| Wed 10.02.21 | Marcelo Arevalo / Matwe Middelkoop | ESA | NED | | 2-1 | Marcelo Demoliner / Santiago Gonzalez | BRA |  MEX | | 6-71 | 7-66 | 6-3 | 2:46 (116-104) |
| Thu 11.02.21 | Miomir Kecmanovic / Casper Ruud | SRB | NOR | | 2-1 | Robin Haase / Oliver Marach | NED | AUT | 13 | 6-3 | 1-6 | 6-0 | 1:16 (66-53) |
| Thu 11.02.21 | Simone Bolelli / Maximo Gonzalez | ITA | ARG | | 2-0 | Jeremy Chardy / Fabrice Martin | FRA | FRA | 12 | 6-3 | 6-4 | | 1:07 (57-41) |
| Wed 10.02.21 | Lorenzo Sonego / Andres Vavassori | ITA | ITA | | 2-1 | Romain Arneodo / Benoit Paire | FRA | FRA | | 6-77 | 6-2 | 6-4 | 2:23 (116-101) |
| Wed 10.02.21 | Laslo Djere / Stefano Travaglia | SRB | ITA | | 2-0 | Andrew Harris / Alexei Popyrin | AUS | AUS | WC | 6-3 | 6-4 | | 1:07 (65-48) |
| Wed 10.02.21 | Jamie Murray / Bruno Soares | GBR | BRA | 6 | 2-0 | M Giron / Cameron Norrie | USA | GBR | | 7-66 | 6-3 | | 1:27 (80-67) |
| Thu 11.02.21 | Nicholas Monroe / Frances Tiafoe | USA | USA | | 2-0 | Marcel Granollers / Horacio Zeballos |  ESP | ARG | 3 | 7-5 | 6-4 | | 1:20 (68-58) |
| Thu 11.02.21 | Vasek Pospisil / Denis Shapovalov | CAN | CAN | | 2-0 | Andrej Martin / T Weissborn | SVK | AUT | ALT | 6-3 | 7-63 | | 1:28 (77-61) |
| Thu 11.02.21 | Marcus Daniell / Philipp Oswald | NZL | AUT | | 2-0 | Adrian Mannarino / Gilles Simon | FRA | FRA | | 6-4 | 6-2 | | 1:04 (62-41) |
| Thu 11.02.21 | Dominik Koepfer / Tennys Sandgren | GER | USA | | 2-1 | Sander Gille / Joran Vliegen |  BEL | BEL | 14 | 6-74 | 6-2 | 7-68 | 2:05 (104-98) |
| Wed 10.02.21 | John Peers / Michael Venus | AUS | NZL | 10 | 2-0 | Alex de Minaur / Matt Reid | AUS | AUS | | 6-3 | 6-2 | | 1:05 (64-48) |
| Wed 10.02.21 | Nam Ji-Sung / Song Min-Kyu | KOR | KOR | WC | 2-0 | Rohan Bopanna / Ben Mclachlan |  IND |  JPN | | 6-4 | 7-60 | | 1:19 (69-57) |
| Fri 12.02.21 | Tomislav Brkic / Aisam Ul-Haq Qureshi | BIH | PAK | | 2-1 | Pablo Andujar / Pedro Martinez Portero | ESP | ESP | | 6-3 | 6-74 | 6-1 | 2:11 (103-81) |
| Thu 11.02.21 | Rajeev Ram / Joe Salisbury | USA | GBR | 5 | 2-0 | Jonny O'Mara / Artem Sitak | GBR | NZL | | 6-4 | 6-4 | | 1:14 (64-49) |
| Thu 11.02.21 | Marcelo Melo / Horia Tecau | BRA | ROU | 7 | ret. | Filip Krajinovic / Dusan Lajovic | SRB | SRB | | 3-0 | retired | 0:16 (13-7) |
| Wed 10.02.21 | Radu Albot / Daniel Evans | MDA | MDA | | 2-0 | Andres Molteni / Hugo Nys | ARG | FRA | | 6-2 | 6-3 | | 1:07 (63-46) |
| Thu 11.02.21 | Luke Bambridge / Dominic Inglot | GBR | GBR | | 2-1 | Aljaz Bedene / Jiri Vesely |  SLO |  CZE | | 6-72 | 7-65 | 7-67 | 2:45 (127-120) |
| Thu 11.02.21 | Ivan Dodig / Filip Polasek | CRO | SVK | 9 | 2-0 | Pablo Carreno Busta / Marc Lopez | ESP | ESP | | 6-1 | 6-3 | | 0:56 (56-32) |
| Wed 12.02.21 | Max Purcell / Luke Saville | AUS | AUS | 15 | 2-0 | Guilermo Duran / Albert Ramos-Vinolas | ARG | ESP | | 6-3 | 6-3 | | 1:07 (62-46) |
| Wed 10.02.21 | Matthew Ebden / John-Patrick Smith | AUS | AUS | WC | 2-1 | Pablo Cuevas / Guido Pella |  URU | ARG | | 6-71 | 6-4 | 6-4 | 2:01 (94-96) |
| Sat 13.02.21 | Thanasi Kokkinakis / Nick Kyrgios | AUS | AUS | WC | 0-0 | George Lloyd Harris / Julina Knowle |  RSA | AUT | 4 | 6-2 | 6-4 | | 1:02 (58-46) |
| Thu 11.02.21 | Wesley Koolhof / Lukasz Kubot | NED | POL | 4 | 2-0 | Ariel Behar / Gonzalo Escobar | URU |  ECU | | 6-3 | 6-4 | | 1:34 (68-57) |
| Wed 10.02.21 | Pierre-Hugues Herbert / Nicolas Mahut | FRA | FRA | 8 | 2-0 | Gianlica Mager / Yoshihito Nishioka | ITA | JPN | ALT | 6-2 | 6-3 | | 1:07 (68-39) |
| Thu 11.02.21 | Yannick Hanfmann / Kevin Krawietz | GER | GER | | 2-0 | Divij Sharan / Igor Zelenay | IND | SVK | | 6-1 | 6-4 | | 1:06 (63-42) |
| Thu 11.02.21 | James Duckworth / Marc Polmans | AUS | AUS | WC | 2-0 | Nikola Cacic / Frederik Nielsen | SRB |  DEN | | 6-4 | 6-4 | | 1:07 (61-50) |
| Wed 10.02.21 | Richard Berankis / Mikhail Kukushkin | LTU | KAZ | | 2-0 | Henri Kontinen / Edouard Roger-Vasselin | FIN | FRA | 11 | 7-5 | 6-4 | | 1:37 (76-66) |
| Thu 11.02.21 | Ken Skupski / Neal Skupski | GBR |  BGR | 16 | 2-0 | Felix Auger Aliassime / Hubert Hurkacz | CAN | POL | | 6-3 | 6-2 | | 1:08 (62-38) |
| Thu 11.02.21 | John Millman / Thiago Monteiro | AUS | BRA | | 2-0 | Federico Coria / Diego Schwartzman | ARG | ARG | | 7-65 | 6-1 | | 1:21 (69-56) |
| Wed 10.02.21 | Mackenzie McDonald / Tommy Paul | USA | USA | | 2-1 | Petros Tsitsipas / Stefanos Tsitsipas |  GRE | GRE | WC | 6-4 | 3-6 | 6-4 | 1:46 (81-86) |
| Wed 10.02.21 | Nikola Mektic / Mate Pavic | CRO | CRO | 2 | 2-0 | Yen-Hsun Lu / Sam Querrey |  TPE | USA | | 7-64 | 6-3 | | 1:10 (66-51) |
